We recently upgraded to 22.214.171.124 and there are some issues with IE10. By default, IE10 is running in compatibility view, but even with it turned off, there are some issues on forms.
I noticed that the file upload is not working properly due to TRIRIGA calling the trim() function in the upload JS (we have some file extensions that we want to exclude and the code gets here). Are there any patches out there that make the product work as expected? IE10 is supported in the compatibility matrix.